Symposium on Pharmaceutical Products
| Co-Chairs: |
Matthew Todd, Johnson & Johnson |
| |
Simon Gaisford, University of London |
Plenary Lecture
Molecular Basis for Increased Sensitivity of Atazanavir-Resistant
HIV I50L Mutant Strains to Other Protease Inhibitors
Dr. Michael L. Doyle, Bristol-Meyers Squibb
Invited Lectures
Non-Linear Temperature Dependence of Enthalpy for Ligand Binding to Thrombin: Temperature-Dependent Heat Capacity Effects or Coupled Folding Event?
Dr. Jose Clemente, GSK
Thermal Stability and Shift Assays in Drug Discovery: Evaluating Protein Constructs and their Functional Properties by Calorimetric Techniques
Dr. James Kranz, Johnson & Johnson
Thermodynamics as a Tool to Impact Ligand-Design Strategy
Dr. Kartik Narayan, Merck
Finding a Needle in a Haystack: Dealing with Complexity in Calorimetric Data.
Michael A. O’Neill, University of Bath, England
TBA
Dr. Rama Shmeis, Sanofi-Aventis
Thermodynamic Studies on the Role of DPP-IV Catalytic Residues in Saxagliptin Binding
Dr. Joseph Yanchunas, Bristol-Meyers Squibb